Insulin receptor molecule, illustration

---

Illustration of the ectodomain of the insulin receptor complexed with bovine insulin and the antigen-binding fragment (Fab) of an antibody. The insulin receptor is a transmembrane protein. The ectodomain is the part of the receptor that sits on the outside of the cell. Binding of insulin to the extracellular part of the protein activates a number of changes inside the cell that lead to the uptake of glucose, the synthesis of glycogen and fatty acids and glycolysis, the production of energy from glucose.

---

Size: 4711px × 4735px
Location:
Photo credit: © FRANCISCO J. ENGUITA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No

Keywords: -, antibody, antigen-binding, artwork, background, binding, biochemical, biochemistry, biological, biology, bound, bovine, complex, complexed, ectodomain, extracellular, fab, fragment, glucose, homoeostasis, illustration, insulin, kinase, metabolism, model, molecular, molecule, protein, receptor, signal, structure, transduction, transmembrane, tyrosine, yellow