Orf Virus, TEM


Negative-stained transmission electron micrograph (TEM) image depicted the ultrastructural details of an Orf virus, a member of the genus Parapoxvirus. Note the spiral arrangement of the external tubular ridges on the ovoid-shaped virus particle, or virion. The Orf virus is a pathogen common to sheep and goats, but can at times be transmitted to humans, in which case the virus is known as being zoonotic. When a human being becomes infected, the symptoms are mainly confined to the skin, and consist of weeping nodules manifesting upon the dorsum, or back of the hands, and which heal in approximately thirty-five days in a spontaneous fashion.


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