. Cellular toxins; or, The chemical factors in the causation of disease. Poisons; Pathology; Bacteria. 130 THE LYSINS. Fig. DemonBtrating Ehrlich's Theory. A, complement; B, intermediary Body ; part of cell; JS, toxophorous group of toxin ; F, haptophorous group. C, receptor; B, If there be no receptors the intermediary body cannot combine with the corpuscle and consequently there is no hemolysis. Anti- hemolysins are supposed to be formed in the body of the animal treated with hemolytic serum in the same way that antitoxins are formed in the bodies of animals immunized to the toxin
. Cellular toxins; or, The chemical factors in the causation of disease. Poisons; Pathology; Bacteria. 130 THE LYSINS. Fig. DemonBtrating Ehrlich's Theory. A, complement; B, intermediary Body ; part of cell; JS, toxophorous group of toxin ; F, haptophorous group. C, receptor; B, If there be no receptors the intermediary body cannot combine with the corpuscle and consequently there is no hemolysis. Anti- hemolysins are supposed to be formed in the body of the animal treated with hemolytic serum in the same way that antitoxins are formed in the bodies of animals immunized to the toxins. If a hemolytic serum be injected into an animal in small but gradually increased doses at intervals, immunity to such serum is obtained and the serum of the animal thus immunized contains an anti-hemolysin. When a small amount of the hemolytic serum is injected it is taken up by the receptor in the blood cell, and provided that the amount of the hemolytic serum injected is small, the blood corpuscle is not destroyed; and needing for the performance of its function the re- ceptor which has combined with the hemolysin, it throws out other receptors; and as in the case of the production of antitoxin, a point is reached when there is over-production of receptors and those not needed by the cell and not taken up by the hemolysin are cast off in the blood and constitute the anti-hemolysin. Ehrlich and Morgen- roth prepared an anti-isolysin in the following manner : A small goat (No. 10) whose blood corpuscles had been shown to be highly susceptible to the serum of goat A was treated at intervals with this serum and an anti-body obtained. When of the serum of goat No. 10 was added to one of a five per cent, dilution of the blood of a goat which had been found susceptible to the serum of goat A, no hemolysis occurred. However, when the blood corpuscles of goat. Please note that these images are extracted from scanned page images that may have been digitally enhanced fo
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