. History and pathology of vaccination. is great strength of mind, made the experiment from theCow on his wife and two sons in the year 1774. The anxiety which Jesty must have felt when hisinoculations were in progress, can be well understood inthe light of later experiences. Those severe symptomsoccurred, which have so commonly followed the useof lymph direct from the cow. Fever ran high withhis patients, and he was obliged to call in medicalaid ; in fact, he met with similar occurrences to thosewhich many years afterwards alarmed Jenner, Bousquet,Estlin, and others to whose lot it has fallen


. History and pathology of vaccination. is great strength of mind, made the experiment from theCow on his wife and two sons in the year 1774. The anxiety which Jesty must have felt when hisinoculations were in progress, can be well understood inthe light of later experiences. Those severe symptomsoccurred, which have so commonly followed the useof lymph direct from the cow. Fever ran high withhis patients, and he was obliged to call in medicalaid ; in fact, he met with similar occurrences to thosewhich many years afterwards alarmed Jenner, Bousquet,Estlin, and others to whose lot it has fallen to observethe full effects of the Cow Pox virus. TRADITIONS OF TIIK DAIRYMAIDS. 123 Mrs. Jesty, who was thus the first person knownto have been intentionally Cow Poxed, not only re-covered from the operation, but lived to the age ofeighty-four, a result which if it was not actuallycredited to the beneficial effects on the constitutionalleged to follow the operation, was certainly testimonythat it had produced no permanent ill Elizabeth jEbXV. Inoculated with Cow Pox in 1774. Mrs. Jesty was buried by the side of her husbandin the churchyard of Worth Matravers, and her tomb-stone bears the following inscription :— Sacred to tin: Memory of ELIZABETH JESTY, Relict of the late BENJAMIN JESTY, of Downshay, who departed this life, Jan. 8, 1824, Aged 84 Years. 124 cow POX A AW SAIALL POX. To the descendants of Jesty, still living in Dorset-shire, I am indebted for the copy of the portrait ofMrs. Jesty, which is here reproduced. It affords addi-tional evidence of the fact that the above accountsare records of persons whose existence was not merelyimaginary. CHAPTER VI. LIFE AND LETTERS OF EDWARD JENNER. Edward Jenner was a nativ^e of Berkeley, in Glou-cestershire. He was born in 1749, and was the thirdson of the Rev. Stephen Jenner, ,, Vicar ofBerkeley. Jenners father had been tutor to a formerEarl of Berkeley, who had a great regard for all thefamily. In the Berkeley


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