. Medical diagnosis for the student and practitioner. icabsorption. But little is definitely known with respect to its functionsdespite the excellent work of many workers during the past few years. There is much to support the belief that it is the main center for bodygrowth and that it bears some curious but little understood relation to thethyroid and suprarenal glands. A relation between gigantism and acromegaly has been suggested and isprobable. It would seem possible that as suggested by Brissaud andMeige, if the hyperpituitarism occurs in childhood, gigantism results, butif delayed until
. Medical diagnosis for the student and practitioner. icabsorption. But little is definitely known with respect to its functionsdespite the excellent work of many workers during the past few years. There is much to support the belief that it is the main center for bodygrowth and that it bears some curious but little understood relation to thethyroid and suprarenal glands. A relation between gigantism and acromegaly has been suggested and isprobable. It would seem possible that as suggested by Brissaud andMeige, if the hyperpituitarism occurs in childhood, gigantism results, butif delayed until ossification of the epiphysis is complete, acromegalicchanges occur.* The disease occurs more frequently in women than inmen, usually begins in early adult life, almost never after the age of forty,and no recognized preexisting disease has been definitely connected with it. * This is denied by Falta and others who insist that hyperpituitarism alone does notproduce gigantism and that acromegaly may occur while the epiphyseal junctures are Fig. 57.—Acromegaly showing enlarged andclumsy bones (case of L. G.). DISEASES OF THE GLANDS OF INTERNAL SECRETION ?l«5 SYMPTOMS.—If well-developed, it is essentially a case for street-car diagnosis, being easily recognized by its outward signs. The face iselliptical in form, the superciliary ridges being prominent, the head oftenlarge and massive, the lower jaw prognathic, the features enlarged andcoarse also by reason of the marked thickening of the greasy integument,in which appear deep creases, especially marked across the forehead. In many cases even thelids are thick and coarse, thehands and feet are enormouslyenlarged, the ringers are spatu-late and clumsy, and upon ex-amination the increase isfound to depend upon thebony overgrowth, a rindingeasily verified by the growth may extend for aconsiderable distance upwardalong the bones of the fore-arm and leg, and sooner orlater tends to involve theclavicles, scap
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Keywords: ., bookcentury1900, bookdecade1920, booksubjectdiagnos, bookyear1922