. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . m. was found attached to its walls, which,after sectioning, proved to be a strangulated embryo. It wasimbedded and cut into serial sections. 14 212 MALL. [Vol. XIX. The sections prove the mass to be an embryo of the fifthweek, filled and covered with round cells. These cells haveobliterated the structure of the head entirely, but as the tailend of the body is approached the outline of the organs canstill be defined. The villi of the chorion are developed in agre


. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . m. was found attached to its walls, which,after sectioning, proved to be a strangulated embryo. It wasimbedded and cut into serial sections. 14 212 MALL. [Vol. XIX. The sections prove the mass to be an embryo of the fifthweek, filled and covered with round cells. These cells haveobliterated the structure of the head entirely, but as the tailend of the body is approached the outline of the organs canstill be defined. The villi of the chorion are developed in agreat mass of blood and pus; the syncytium is the stroma of the villi there are, at many points, manyround cells which appear to be migrating cells from theembryo. No. 162. Mole, 70 x 30 x 30 mm.; embryo, 1 mm. Dr. Wanstall, Baltimore. The specimen came to me in formalin with the followingnote from Dr. Wanstall: Last period from September 2 to7, that is her usual time, five days. The woman began bleed-ing November 9, and passed the specimen on November 22She is the mother of five children and says that this is the. Fig. 162.—Section through the embryo. X 15 times. Ch, chorion; am,amnion; h, heart; umb, umbilical vesicle; in, intestine; all, allantoisor possibly liver. only time she has aborted. There is not the slightest indica-tion of uterine disease. Within the specimen there is a cavity measuring 35 x 12 x12 mm., lined with a smooth wall and filled with a jelly-likesubstance, within which there is a very small embryo whichwas cut into serial sections 50 microns thick. The sectionsshow a remarkable atrophy of the embryo and umbilicalvesicle. The chorion is very thin and is composed of meso- No. i.] ORIGIN OF HUMAN MONSTERS. 213 derm only. The villi and epithelial cells are wanting-, but intheir place there is a thick layer of mothers blood. The entirechorion is lined with an amnion and into its cavity the nodule-like embryo projects. Its tissues are not unifor


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