. Medical diagnosis for the student and practitioner. fferentiate it. Prognosis.—This varies according to the cause. Many cases may beentirely cured; others, never. GASTRIC AND DUODENAL ULCER 907 GASTRIC AND DUODENAL (POST-PYLORIC) ULCER GASTRIC ULCER.—Definition.—An ulcer of the gastric mucous mem-brane, usually single but often multiple and tending either to an acute coursefollowed by complete or partial healing, extreme chronicity, or, to perforation,either prompt or long delayed. As to ulcers in close proximity to the pyloric ring, whether proximal or distal,no distinct line can or need be


. Medical diagnosis for the student and practitioner. fferentiate it. Prognosis.—This varies according to the cause. Many cases may beentirely cured; others, never. GASTRIC AND DUODENAL ULCER 907 GASTRIC AND DUODENAL (POST-PYLORIC) ULCER GASTRIC ULCER.—Definition.—An ulcer of the gastric mucous mem-brane, usually single but often multiple and tending either to an acute coursefollowed by complete or partial healing, extreme chronicity, or, to perforation,either prompt or long delayed. As to ulcers in close proximity to the pyloric ring, whether proximal or distal,no distinct line can or need be drawn. The so-called duodenal ulcer is actuallya post-pyloric gastric lesion, for in 95 per cent, of all such cases it occupies thefirst portion of the duodenum, embryologically and anatomically an integralpart of the stomach. Etiology.—Aside from direct irritation or traumatism, toxemia, hyper-acidity with deficient mucous secretion and devitalizing anemia, appear tobe the most important associated conditions. The true cause is not known,*. Fig. 463.—Prepyloric acute ulcer with total spasm of the pyloric antrum and decidedretention. Such a case would show high HC1 values. (After von Bergmann.) but the organisms contained in cryptogenetic septic foci may prove theimportant antecedent factors or even the determining causes. All of theolder theories are imperfect and unconvincing. Both anemia and toxemia are factors in delayed healing. Sex.—About 60 per cent, of acute gastric ulcers occur in females. Thechronic forms on the other hand show decided male predominance. Age.—It occurs most commonly between the ages of twenty to forty,least often, yet occasionally, in babies, f young children, and elderly persons,and there is probably little or no hereditary element. Acute ulceration is encountered chiefly between the ages of 20 and 70 per cent, of all ulcers are recognized between the ages of 30 and between the age periods of 50 to 60 and 60 to 70 there


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Keywords: ., bookcentury1900, bookdecade1920, booksubjectdiagnos, bookyear1922