. The eggs of mammals . Fig. 15. Ovum removed from a preovulatory follicle of an unmated rabbit showing the vesicular nucleus. (From the Journal of Experimental Medicine.) ovum. That is that the production of the first polar body is dependent upon stimulation by pituitary hormones. Since this phenomenon is of some consequence to any discussion of the activation of mammalian eggs the writer, in collaboration with Dr. E. V. Enzmann (Pincus and Enz- mann, 1935), has undertaken an examination of the mecha- nism of polar body formation in the rabbit ovary. The rabbit was chosen for these experiment


. The eggs of mammals . Fig. 15. Ovum removed from a preovulatory follicle of an unmated rabbit showing the vesicular nucleus. (From the Journal of Experimental Medicine.) ovum. That is that the production of the first polar body is dependent upon stimulation by pituitary hormones. Since this phenomenon is of some consequence to any discussion of the activation of mammalian eggs the writer, in collaboration with Dr. E. V. Enzmann (Pincus and Enz- mann, 1935), has undertaken an examination of the mecha- nism of polar body formation in the rabbit ovary. The rabbit was chosen for these experiments because it ovulates only after copulation and the ova are liberated regularly between 93^ and 103^ hours after copulation (see Heape, 1905; Walton and Hammond, 1932; Pincus, 1930; Pincus and Enzmann, 1932). Furthermore, the mature ova form polar bodies only after copulation. According to Heape (1905)


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