. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 250 C. L. PROSSER AND C. L. JUDSON tude of the effect in the concentration range 10~10 to 10~G varied considerably and it is not likely that the Stichopus vessel, despite its high sensitivity, would make a satisfactory assay material for acetylcholine. Physostigmine in moderate concentrations inhibited the vessel, but a concentra- tion of 10~10 in sea water had no effect alone; however, after treatment with this concentration of eserine, acetylcholine at 10~1G, which had previously been ineffective, caused a 25 per cent slow
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 250 C. L. PROSSER AND C. L. JUDSON tude of the effect in the concentration range 10~10 to 10~G varied considerably and it is not likely that the Stichopus vessel, despite its high sensitivity, would make a satisfactory assay material for acetylcholine. Physostigmine in moderate concentrations inhibited the vessel, but a concentra- tion of 10~10 in sea water had no effect alone; however, after treatment with this concentration of eserine, acetylcholine at 10~1G, which had previously been ineffective, caused a 25 per cent slowing. Nicotine inhibits the Stichopus vessel. Thresholds varied, but in two prepara- tions, significant inhibition was observed at a dilution of 10"11. One preparation gave the following percentages of inhibition at the dilutions indicated: 10 9, 15 per cent; 1O8, 43 per cent; 10~7, 57 per cent; 10~c, total cessation of beat. V- '* *• .-"•' •* * f • • » ••w* • •. PLATE I. Sections of vessels of Sticliopns californicits. X 80. E—epithelium; M—cir- cular muscle; C—connective tissue ; B—region of formation of blood cells. FIGURE 1. Cross section of small branch vessel. FIGURE 2. Longitudinal section close to edge of wall of large vessel. FIGURE 3. Longitudinal section through center of vessel. FIGURE 4. Longitudinal section in region of Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Clarence, 1890-1983. Woods Hole, Mass. : Marine Biological Laboratory
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