. The principles of surgery . OSTEOSARCOMA. 455. radiating in spicula outwards, which diverge, and interlace—leavinginterstices, more or less wide, in which the fleshy substance is lodged. The interstitial structure is of different kinds. In some cases, it ispartly cartilaginous; in others, of a fibrous character, or resemblingthe simple sarcoma; in others it is cystic. Most frequently, it is com-posed of sarcomatous substance, containing occasional points of carti-lage. Cells, too, are usually found; be-ing probably certain of the interstices,dilated, and unoccupied by solid matter;filled wit


. The principles of surgery . OSTEOSARCOMA. 455. radiating in spicula outwards, which diverge, and interlace—leavinginterstices, more or less wide, in which the fleshy substance is lodged. The interstitial structure is of different kinds. In some cases, it ispartly cartilaginous; in others, of a fibrous character, or resemblingthe simple sarcoma; in others it is cystic. Most frequently, it is com-posed of sarcomatous substance, containing occasional points of carti-lage. Cells, too, are usually found; be-ing probably certain of the interstices,dilated, and unoccupied by solid matter;filled with fluid, sometimes glairy andclear, sometimes serous and turbid. Theyare seldom of large size, but may be nu-merous. Being lined by a secreting membrane,these cysts constitute the most dangerouspart of the tumour. On perversion oftheir action, degeneration would seem todepend. In proportion as this growth in the in-terior of the bone is developed, the exte-rior shell becomes expanded. And, as inenchondroma, the latter for a time retainsits co


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