. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 150- 100-. 12 24 36 48 60 12 24 36 48 60 72 84 96 Time, hr FIGURE 6. Rhythms of melatonin release from isolated perfused chicken pineals. A and B are in light-dark cycles and C and D are in constant dim red light (1-5 lux). Each record is from one pineal. In the constant dim light the rhythms persist, although damped, showing the presence of an endogenously timed release mechanism. From Takahaski et a/., 1980. endogenous circadian rhythm in constant darkness. It entrained to a reversed pho- tocycle. This establishes that the
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 150- 100-. 12 24 36 48 60 12 24 36 48 60 72 84 96 Time, hr FIGURE 6. Rhythms of melatonin release from isolated perfused chicken pineals. A and B are in light-dark cycles and C and D are in constant dim red light (1-5 lux). Each record is from one pineal. In the constant dim light the rhythms persist, although damped, showing the presence of an endogenously timed release mechanism. From Takahaski et a/., 1980. endogenous circadian rhythm in constant darkness. It entrained to a reversed pho- tocycle. This establishes that the cell culture contains both a circadian clock and the photoreceptor that entrains the clock to light. Since the dissociated pinealocytes are not in an organized tissue, these results also suggest that each cell has its own photoreceptor and circadian oscillator, coupled to the enzyme NAT. Romero et al. (1975) blocked the rat pineal's rise in NAT activity in darkness with cyclo-. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Clarence, 1890-1983. Woods Hole, Mass. : Marine Biological Laboratory
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