. Röntgen ray diagnosis and therapy . iation. shows the tumourous area in adenocarcinoma of the breastbefore irradiation, while Fig. 272 demonstrates the same area afterslight reaction had set in. In the latter colloid degeneration isbeginning. A resemblance to glandular structure is shown. Inmost parts the alveoli are completely filled with epithelial cells, sothat in some places they appear like alveolar carcinoma, Some SPECIAL INDICATIONS 393 areas have undergone degeneration, their epithelial cells no! taking on the stain the same as others. The cells have diminished in sizeand the
. Röntgen ray diagnosis and therapy . iation. shows the tumourous area in adenocarcinoma of the breastbefore irradiation, while Fig. 272 demonstrates the same area afterslight reaction had set in. In the latter colloid degeneration isbeginning. A resemblance to glandular structure is shown. Inmost parts the alveoli are completely filled with epithelial cells, sothat in some places they appear like alveolar carcinoma, Some SPECIAL INDICATIONS 393 areas have undergone degeneration, their epithelial cells no! taking on the stain the same as others. The cells have diminished in sizeand the degenerated area, excepi the nuclei, appears coarsely gran-ular. Changes of the same nature arc observed in the epithelium ofthe skin covering the tumour (also due to the action of the rays).In some parts of the necrotic area a large amounl of dense con-nective tissue and marked vascularity are noticed. In the treatment of the skin diseases described above, tentativeexposures, and protection of the vicinity of the affected area were. Pig. 271.—Carcinomatous Area, not affected by the Rays.(Compare Fig 272.) advised. The distance of the tube was not less than 4 inches inthe beginning, the duration ten minutes, and the intervals two tothree clays on an average. In treating malignant diseases we should be governed by entire-ly different principles. The author has emphasized repeatedly thatnothing appears more absurd than protecting the area which de-mands the influence of a sort of destroying agent. Since Volkmannfound, on microscopical examination, that even in small and super-ficially located carcinomatous growths of the mammary gland, the 394 THE EONTGEK EAYS fascia was generally involved, he was naturally led to the conclu-sion that removal of the tumour alone was an insufficient pro-cedure. The correctness of his investigations was corroborated byHeidenhain, who found carcinomatous cells in the superficiallayer of the pectoralis major muscle, even when the breast wasonly s
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