. Textbook of pastoral and agricultural botany, for the study of the injurious and useful plants of country and farm. lethaldose for guinea-pigs, and is anti-hemolytic for the hemolysin of Amanita,when diluted to i-iooo. As he and Abel had found this hemolytic poison of A manita phalloides to be a glu-coside, this observation is to beinterpreted as a successful pro-duction of an antibody for anon-protein poison, a substance corresponds tothe phallin of Kobert, which isusually given as the activeprinciple of this deadly toad-stool. Wells suggests that prob-ably this hemolytic poi
. Textbook of pastoral and agricultural botany, for the study of the injurious and useful plants of country and farm. lethaldose for guinea-pigs, and is anti-hemolytic for the hemolysin of Amanita,when diluted to i-iooo. As he and Abel had found this hemolytic poison of A manita phalloides to be a glu-coside, this observation is to beinterpreted as a successful pro-duction of an antibody for anon-protein poison, a substance corresponds tothe phallin of Kobert, which isusually given as the activeprinciple of this deadly toad-stool. Wells suggests that prob-ably this hemolytic poison isnot the important agent inpoisoning by Amanita phalloides,as it is easily destroyed by heatand the digestive fluids. Thethermostable poison, amanita-toxin, gives no reactions foreither glucosides, or proteins anddoes not confer any antitoxicproperty to the blood of im-munized animals. Amanita-toxin kills acutely, the animalsdying in 24-48 hours, and show-ing no changes beyond a fattydegeneration of the internal or-gans. The hemolysin killsslowly in three to ten days,causing local edema and Fig. 13.—Amanita phalloides. {AfterPatterson, Flora W. and Charles, Vera K.:Mushrooms and other Common Fungi,Bull. 75, U. S. Department of Agriculture,1915, Fig. 2.) Symptoms.—V. K. Chestnut gives a synopsis of the symptoms ofpoisoning by Amanita phalloides. The fundamental injury is not due,as in the case of muscarin, to a paralysis of the nerves controlling theaction of the heart, but to a direct effect on the blood corpuscles (see above)These are quickly dissolved by phallin, the blood serum escaping from theblood vessels into the alimentary canal, and the whole system being POISONOUS FUNGI AND OTHER SPORE-BEARING PLANTS 37 rapidly drained of its vitality. No bad taste warns the victim, nor dothe preliminary symptoms begin until nine to fourteen hours after thepoisonous mushrooms are eaten. There is then considerable abdominalpain and there may be cramps in the
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