The American journal of anatomy . yonic cells described by Meves (08), inasmuch as the onlyformed elements visible in them are thick mitochondrial rods(chondrioconts). The cells of the terminal ductules including the centroacinuscells are richer in fuchsinophile bodies than the cells of the largerintralobular ducts (fig. 14). Much of this fuchsinophile materialis in the form of the characteristic mitochondrial rods, but, inaddition there are irregular spherical or angular granules present 372 R. R. BENSLEY concerning the interpretation of which I am in doubt. Possiblythey represent in part a s


The American journal of anatomy . yonic cells described by Meves (08), inasmuch as the onlyformed elements visible in them are thick mitochondrial rods(chondrioconts). The cells of the terminal ductules including the centroacinuscells are richer in fuchsinophile bodies than the cells of the largerintralobular ducts (fig. 14). Much of this fuchsinophile materialis in the form of the characteristic mitochondrial rods, but, inaddition there are irregular spherical or angular granules present 372 R. R. BENSLEY concerning the interpretation of which I am in doubt. Possiblythey represent in part a secretion antecedent. TRANSITIONS BETWEEN ACINUS CELLS AND ISLET CELLS Having now defined the islet cell as an element containing gran-ules which are peculiar to each type of cell composing the islet,and which occur in no other cell of the pancreas, it is possible todiscuss on this basis the question of what should be accepted as ascientific demonstration of cells which are intermediate in typebetween islet cells and acinus Fig. 14 Section of an acinus of the pancreas of the guinea pig, showing centro-acinous cells with mitochondria and fuchsinophile bodies. In the acinus cellsmay be seen, zymogen granules, and long mitochondrial filaments. Acetic osmicbichromate, anilin acid fuchsin, methyl green. X 1555. It has been shown that the acinus cells have two constituentswhich are not present in the islet cell, namely zymogen granulesand basophile substance, and also that each type of islet cell con-tains granules which are peculiar to itself and which are not pres-ent in the cells of the acini. Tt has also been shown that the ductcell contains neither the specific constituents of the acinus cellnor those of either islet cell. The mitochondria, moreover, whilepresent in all four types have characters of their own for each type. STUDIES ON THE PANCREAS OF THE GUINEA PIG 373 The question we now have to consider is: If a cell of an acinuswere being transformed into an islet cell


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Keywords: ., bookcentury1900, bookdecade1900, booksubjectanatomy, bookyear1901