. Electron microscopy; proceedings of the Stockholm Conference, September, 1956. Electron microscopy. Chick Embryo Thyroid 173. Fig. 2. Section through the basal part of a thyroid cell and a capillary showing endothelial discontinuities. BM = base- ment membrane: END -â ^- endothelium: RB -- red blood corpuscle. Magnification 62,C00. more or less distinct fairly dense membrane and the endothelial basement membrane continues uninter- rupted over these areas. The width of the discon- tinuities is about 300 A. References 1. Braunsteiner, H., Fellinger, K., and Pakesch, F., Endocrinology 53, 123 (
. Electron microscopy; proceedings of the Stockholm Conference, September, 1956. Electron microscopy. Chick Embryo Thyroid 173. Fig. 2. Section through the basal part of a thyroid cell and a capillary showing endothelial discontinuities. BM = base- ment membrane: END -â ^- endothelium: RB -- red blood corpuscle. Magnification 62,C00. more or less distinct fairly dense membrane and the endothelial basement membrane continues uninter- rupted over these areas. The width of the discon- tinuities is about 300 A. References 1. Braunsteiner, H., Fellinger, K., and Pakesch, F., Endocrinology 53, 123 (1953). 2. Dempsey, E. W. and Pi n rson, R. R., Endociinoloi;y 36, 46 (1955). 3. Ekholm, R. and Zelander, T., Experientia 12. 195 (1956). 4. Monroe, B. G., Anat. Rec. 116, 345 (1953). 5. Newman, S. B., Borysko, E., and Swerdiow, M., J. Research Natl. Bur. Standards 42,, 183 (1949). 6. Palade, G. E., J. Med. 95. 285 (1952). 7. Sjostrand, F. S., Experientia 9, 114 (1953). 8. â //( PoLLiSTER, A. W., Physical techniques in biological research. Vol. III. New York, 1956. Electron Microscopy of Chick Embryo Thyroi(d R. Stole, P. Blanquet, A. P. Lachapele, R. Maraud, and A. Magimel Fondation Bergonie and Facidte de Medecine, Bordeaux According to a previous investigation the differ- entiation of the chick embryo thyroid shows two successive periods (18). In the first one, before 12 days, the thyroid anlage concentrates very low quan- tities of radioiodine and is practically devoid of follicles. During the second one, the uptake of radio- iodine raises suddenly and strongly together with the differentiation of the follicular structure. Differ- ence between the two periods is closely associated with colloid synthesis. The present investigation was undertaken to de- termine to what extent this phenomenon could be related to the development of the c\toplasmic cana- licular structures which were described in the thyroid of adult mammals (4, 14. 15. 23. 24). Normal thyroid glands we
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