. A treatise on the nervous diseases of children : for physicians and students. ositehalf. In consequence ofthe changes going onin the gray matter, thecolumns of Clarke dis-appear, together withother nervous struct-ures. These changesare unquestionably sec-ondary to the changesin the anterior horns,and considering the intimate relation between the anteriorhorns and the remaining part of the gray matter, as hasbeen brought to light by recent anatomical investigations,we can readily understand why, in consequence of diseasein one part of the gray matter causing destruction of nerve-cells, the ne
. A treatise on the nervous diseases of children : for physicians and students. ositehalf. In consequence ofthe changes going onin the gray matter, thecolumns of Clarke dis-appear, together withother nervous struct-ures. These changesare unquestionably sec-ondary to the changesin the anterior horns,and considering the intimate relation between the anteriorhorns and the remaining part of the gray matter, as hasbeen brought to light by recent anatomical investigations,we can readily understand why, in consequence of diseasein one part of the gray matter causing destruction of nerve-cells, the nerve-fibres which owe their life and nutrition tosuch cells disappear as well. The anterior nerve-roots aresmaller than the corresponding roots of the sound changes are also, in all probability, secondary to thechanges in the ganglion cells. So much for the changes to be observed in the spinalcord itself. The atrophied muscles also present character-istic conditions. The fibres are very much diminished in size,many of them have disappeared altogether, and the place. Fig. 79.—Poliomyelitis Anterior. Chronic stage ;section through sixth cervical segment, showingdiminution of anterior gray matter and of en-tire half of right side. (Drawn from a specimenkindly furnished me by Dr. Collins.) INFANTILE SPINAL PARALYSIS. 303 once occupied by the normal fibres is largely filled by adi-pose tissue. There is in these cases no such nuclear prolif-eration and no hypertrophy of fibres such as are found inthe muscles of patients suffering from various forms ofmuscular dystrophy. But even the presence of a fewhypertrophied fibres would not be unusual, as the stage ofhypertrophy seems to indicate an incipient irritation whichprecedes the condition of atrophy. Marie has gone to sometrouble to show that even the bones in cases of poliomye-litis undergo trOphic changes. The bones are smaller thanthose of the corresponding healthy member and appearmore rounded on cross-section than the
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Keywords: ., bookcentury1800, bookdecade1890, bookpublishernewyo, bookyear1895
