. Ciba Foundation colloquia on ageing. Old age; Aging; Animals -- growth & development. Development of Acid-Base Control 215 it is evidently lower even than the excretion of ammonia. By one year of age the glomerular filtration rate/kg. had risen above that of adults (McCance and Widdowson, 1952), and more ammonia and surplus anions per kg. were being ex- creted (see Figs. 1 and 3); the amount of ammonia excreted per ml. of glomerular filtrate was near the adult level. 08 0-7 0-6 0-5 t O 3 0-2 Ol. Adult Before O- 24- 7- I birth 24h. 48h. Sday year Fig. 4. The ratio of the ammonia excreted
. Ciba Foundation colloquia on ageing. Old age; Aging; Animals -- growth & development. Development of Acid-Base Control 215 it is evidently lower even than the excretion of ammonia. By one year of age the glomerular filtration rate/kg. had risen above that of adults (McCance and Widdowson, 1952), and more ammonia and surplus anions per kg. were being ex- creted (see Figs. 1 and 3); the amount of ammonia excreted per ml. of glomerular filtrate was near the adult level. 08 0-7 0-6 0-5 t O 3 0-2 Ol. Adult Before O- 24- 7- I birth 24h. 48h. Sday year Fig. 4. The ratio of the ammonia excreted (m-mole/24 h.) to the glomerular filtration rate (). The nature of the titratable acidity Fig. 5 shows the excretion of titratable acid per kg. of body weight by the babies and the adults. The amount excreted was low during the whole of the first week, but it was rising even though the urine still contained no phosphates. The high excretion at a year is again related to the high intake of protein at that age. Fig. 6 shows the percentage of the titratable acidity due to phosphate in the urine of an adult and in the urine of a breast- fed baby in the first week of life. In the adult the percentage depends upon the pH and, since the pH of the urine passed. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation; Wolstenholme, G. E. W. (Gordon Ethelbert Ward). Boston, Little, Brown
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