AMAarchives of neurology & psychiatry . t was highly important to attempt to estab-lish the sequence of events with reference to the involvement of the variousstructural units including the myelin sheath of nerve fibers, the axis cylinders,the interstitial supporting glial elements, the ganglion cells of the gray matter,and also the mesodermal structures, particularly the blood vessels. GLOBUS-STRALSS—FUMCULAR MYELOPATHY 371 The Myelin Sheath : Our material showed conclusively and uniformly thatthe myelin sheath was the seat of the most intense disease process. In areasin which the softening p
AMAarchives of neurology & psychiatry . t was highly important to attempt to estab-lish the sequence of events with reference to the involvement of the variousstructural units including the myelin sheath of nerve fibers, the axis cylinders,the interstitial supporting glial elements, the ganglion cells of the gray matter,and also the mesodermal structures, particularly the blood vessels. GLOBUS-STRALSS—FUMCULAR MYELOPATHY 371 The Myelin Sheath : Our material showed conclusively and uniformly thatthe myelin sheath was the seat of the most intense disease process. In areasin which the softening process was most acute, the myelin cover of nerve fibersalmost completely disappeared. The resultant products of destruction werepicked up by phagocytic elements (Fig. 3) which were mainly glial in the myelin still remained it was fragmented and occasionally incor-porated in Marchi bodies. Transitional stages in the degenerative process ofthe myelin were frequently seen in the form of swelling or irregularities %^K* ^^:. # ir
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