. Adventures in radioisotope research;. Radioactive tracers; Radiobiology. 478 ADVENTURES IN RADIOISOTOPE RESEARCH dSr dt = a(Sp —Si) As already mentioned, a is the coefficient of penetration. In an early stage of the experiment the change of s^ and s^ with time is linear and therefore, as far as we choose such experimental conditions that most of the activity is still to be found in the plasma, we arrive at the average value of s^ during the experiment Sp + i —Se P and in analogous way on the average From which follows, considering that s^ increases linearly with time, S, = a(Sp+i —Se —iS,)t.
. Adventures in radioisotope research;. Radioactive tracers; Radiobiology. 478 ADVENTURES IN RADIOISOTOPE RESEARCH dSr dt = a(Sp —Si) As already mentioned, a is the coefficient of penetration. In an early stage of the experiment the change of s^ and s^ with time is linear and therefore, as far as we choose such experimental conditions that most of the activity is still to be found in the plasma, we arrive at the average value of s^ during the experiment Sp + i —Se P and in analogous way on the average From which follows, considering that s^ increases linearly with time, S, = a(Sp+i —Se —iS,)t. We found in our best experiment — = 4 and, as we saw that Sj = S^ P we conclude that the end value of the specific activity of the corpuscles total acid-soluble P when the experiment, as was in our case, is of re- restricted duration, Sc=a(Sp -f The value of the penetration coefficient of the phosphate ions into the corpuscles, a magnitude we shall make use of in our later calculations, is given in Table 2. Table 2. — Calculation of the Penetbation-Coefficient OF Phosphate-Ions (a) into Corpuscles Sp denotes the specific activity of the total acid-soluble P in the corpuscles; Sp that of the plasma at the end of the experiment Time in min. f 170 Rabbit C { ?^,.^^ Rabbit G I ^^ \ 90 Average value Average value (Rabbit C alone). Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Hevesy, Georg von, 1885-1966. New York, Pergamon Press
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