RXR and LXR nuclear receptors and DNA. Molecular model of a strand of DNA (dexyribonucleic acid, yellow) and two nuclear receptors (coiled strands, pr
RXR and LXR nuclear receptors and DNA. Molecular model of a strand of DNA (dexyribonucleic acid, yellow) and two nuclear receptors (coiled strands, proteins) being acted on by drug molecules (space-filled models). At left is a retinoic X receptor (RXR, blue) in a complex with retinoic acid. At right is a liver X receptor (LXR, pale blue) in complex with the drug GW3965. Both receptors can bind to DNA specific sequences to act like master gene regulators. They play a central role in metabolic homeostasis, regulating glucose and lipid pathways. The drugs used on these receptors are studied for use in treating multiple sclerosis, atherosclerosis, diabetes, inflammation, and Alzheimer's disease.
Size: 3620px × 4827px
Photo credit: © RAMON ANDRADE 3DCIENCIA/SCIENCE PHOTO LIBRARY / Alamy / Afripics
License: Licensed
Model Released: No
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