. Dental materia medica and therapeutics; with special reference to the rational application of remedial measures to dental diseases ... r, and apply the hypo-dermic or high pressure syringe, provided with a special needle,making as nearly as possible a water-tight joint. Apply slow,continuous pressure for two or three minutes. With a burr thepulp should now be exposed, and, if still found sensitive, theprocess k to be repeated. Regarding the principle of pressure anesthesia, it should be re-membered that we can not force a liquid through healthy dentinby a mechanical device without injury to


. Dental materia medica and therapeutics; with special reference to the rational application of remedial measures to dental diseases ... r, and apply the hypo-dermic or high pressure syringe, provided with a special needle,making as nearly as possible a water-tight joint. Apply slow,continuous pressure for two or three minutes. With a burr thepulp should now be exposed, and, if still found sensitive, theprocess k to be repeated. Regarding the principle of pressure anesthesia, it should be re-membered that we can not force a liquid through healthy dentinby a mechanical device without injury to the tooth itself. An 1 Miller: Dental Register, 1904, Vol. IV. TECHNIQUE OP THE INJECTION. 493 attempt to force fluids by high pressure through sound livingdentin into a pulp will result in failure. Walkhoff has tried toforce colored solutions into freshly extracted teeth by applyingsix atmospheres pressure for half an hour without success. If acocain solution is held in close contact with the protoplasmicfibers of the dentin, the absorption of cocain takes place in ac-cordance with the laws of osmosis. The imbibition of the anes-. FlGURE 96. An Aqueous Solution of Eosin Forced Through Dentin with a Jewett-Willcox , one and one-half minutes. The pulp is stained. (Miller.) thetic is enhanced by employing a physiologic salt solution as avehicle. Living protoplasm, however, reacts unfavorably againstthe ready absorption of substances by osmosis for two reasons:First, as Graham has shown, the albumin molecule is relativelylarge and not easily diffusible, and, second, as an integral partof its life it possesses vital resistance toward foreign bodies. 494 LOCAL ANESTHESIA. These biologic facts, as stated by Walkhoff,1 describe in a preg-nant manner some of the most important physiologic functionsof the odontoblasts. The accuracy of this dictum is easily dem-onstrated by the fact that it is almost impossible to stain livingtissue, while dead tissue is at once penetrated by


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