. Diet as a factor in length of life and in structure and composition of tissues of the rat with aging. KIDNEY WEIGHT" (grams Regression equation y= + 0J!3x. o Regression equation: y= + 0.!09x JL 8 12 16 20 24 26 LIVER WEIGHT (grams) Figure 8.—Liver weight in relation to kidney weight in fasted and nonfasted rats fed stock diet. or kidney weight to body weight tended to be lower than those for liver and kidney, although for fasted rats the differences observed were generally small. The lowest correlation coefficients were those relating liver or kidney to body weight in nonfasted
. Diet as a factor in length of life and in structure and composition of tissues of the rat with aging. KIDNEY WEIGHT" (grams Regression equation y= + 0J!3x. o Regression equation: y= + 0.!09x JL 8 12 16 20 24 26 LIVER WEIGHT (grams) Figure 8.—Liver weight in relation to kidney weight in fasted and nonfasted rats fed stock diet. or kidney weight to body weight tended to be lower than those for liver and kidney, although for fasted rats the differences observed were generally small. The lowest correlation coefficients were those relating liver or kidney to body weight in nonfasted rats fed the semipurified diet. There was little evidence for a quantitative rela- tionship between liver and kidney weights or be- tween these organs and body weight in rats fed SPE diet. Even in fasted rats, ratios for liver to kidney weight varied from to Kidney weight of animals losing weight on stock, SP 8 HVO, and SPE diets.—In table 25 are summarized data on the kidney weights of fasted and nonfasted rats that were fed stock, SP 8 HVO, or SPE diets and were losing weight when sacrificed. The results for rats losing less than 100 grams have been separated from those for rats losing over 100 grams in weight. When weight loss was less than 100 grams, the kidneys from fasted rats fed stock or SP 8 HVO diets were similar in size to those from rats of comparable age that were maintaining weight on these diets. On SPE diet, however, large kidneys were observed even in young rats, and in animals 400 to 599 days old 68 percent of the kidneys weighed more than 4 grams. When weight loss exceeded 100 grams, the kidneys from fasted rats tended to be larger with all three diets than did those from comparable animals with little or no weight loss. The largest kidneys were from rats fed SPE diet. The tendency of the nonfasted rats to have larger kidneys than the fasted animals was apparent among those that were losing weight, as well as among those maintaining weight, alt
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