A treatise on Bright's disease and diabetes, with especial reference to pathology and therapeuticsIncluding a section on retinitis in Bright's disease . degreeof alteration occurs in any of the forms of Brights in the number of cells, resulting in stratified layers,is a much more rare occurrence, but Langhans has seen it inacute nephritis where there were haemorrhages within the cap-sule. Here the Malpighian body is elongated in a directionparallel with the axis of the medullary rays. This is due tothe presence between the capsule and the glomerule of a cres-centic mass of cel


A treatise on Bright's disease and diabetes, with especial reference to pathology and therapeuticsIncluding a section on retinitis in Bright's disease . degreeof alteration occurs in any of the forms of Brights in the number of cells, resulting in stratified layers,is a much more rare occurrence, but Langhans has seen it inacute nephritis where there were haemorrhages within the cap-sule. Here the Malpighian body is elongated in a directionparallel with the axis of the medullary rays. This is due tothe presence between the capsule and the glomerule of a cres-centic mass of cells, of which the thickest portion is opposite,or nearly opposite, the point of entrance of the vas the spaces between the layers of these cells, which are more * Langhans, Theodore, Ueher die Veriinderungen der Glomeruli beiNephritis nel>st einigen Bemerkungen iiher die Entstehung der Fibrin-cylinder, Virciiows Archiv, Bd. 76, 1879, s. 85. ACUTE PARENCHYMATOUS NEPHRITIS. 95 or less epitheloid in shape, are found smaller and largerlymphoid cells. More frequent than this extreme degree ispartial thickening of the capsular Proliferation and thickening of the capsular epitlieliiim with compression of theglonierule. X 120.—Alter Langhans. With regard to the effect of this proliferation upon the func-tion of the kidney it is not unlikely that by exerting a pressureupon the capillaries of the glomeride it diminishes the quan-tity of urine secreted, especially as in Langhanss cases such adiminution occurred, and especially also as proliferation of theinterstitial tissue in contiacted kidney is attended by an oppositeresult; and alterations of the epithelium of the tubules arenot necessarily attended by such results. The haemorrhageswhich sometimes occur in the Malpighian body where thesealterations exist, Langhans would locate, not in the capillariesof the glomerule itself, but in those of its capsule, since theblood is not found on the surface of the glom


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