. A manual of diseases of the nervous system. ataxic paraplegia is similar to thatin the spastic form, and depends on similar considerations, which neednot be here repeated. Treatment.—The treatment of ataxic paraplegia is the same as thatof the allied diseases, and especially of spastic paraplegia, to the accountof which the reader is referred. SCLEROSIS OF THE CORD FROM TOXIC BLOOD-STATES. Pellagra. Pellagra is an endemic malady which, though fortunately unknownin this country, deserves mention here on account of the incidenceof its effects on the spinal cord. Its chief anatomical lesion is
. A manual of diseases of the nervous system. ataxic paraplegia is similar to thatin the spastic form, and depends on similar considerations, which neednot be here repeated. Treatment.—The treatment of ataxic paraplegia is the same as thatof the allied diseases, and especially of spastic paraplegia, to the accountof which the reader is referred. SCLEROSIS OF THE CORD FROM TOXIC BLOOD-STATES. Pellagra. Pellagra is an endemic malady which, though fortunately unknownin this country, deserves mention here on account of the incidenceof its effects on the spinal cord. Its chief anatomical lesion is adegeneration of the lateral and posterior colunms of the cord, corre-sponding closely to that of ataxic paraplegia, and, as in that disease,with a greater affection of the lateral than of the posterior differs, however, ia the fact that some atrophy of the large nerve-cells of the anterior comua is common, and also in the constancy with * For some instructive notes ou this point in diagnosis see Drescbfeld, Brain,January, 512 SPINAL CORD. whicli chronic inflammation of the pia mater is met with, sometimesaccompanied bj the formation of bony plates in the arachnoid. The Cause of the disease appears to be the action, on the elementsof the spinal corcl, of an organised virus (or of some product of this)which is taken into the system with diseased or unripe maize. Even spirit distilled from such unripe maize i^^n^S^^ _^~~. ^-^Q ^^y cause the disease. The distri- cy^^^-- ~^-~-^ bution of the disease in the north of Italy, where the maize is frequentlygathered unripe, is significant. Thevirus has been thought by some (asLombroso) to be a fungus growingin the maize ; by others to be specificmicro-organisms of other than fun-goid nature, present in the maize,which develop in the system and pro-duce there the toxic agent that has aspecial action on the nerve-elements(Belmondo). The researches of Tuc-zek* have clearly shown that thechange is a sclerosis of the cord d
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