. Bacteriophages. Bacteriophages; Bacteriophages. USE OF PHAGES IN EPIDEMIOLOGICAL STUDIES 405 typical typhoid phage typing plates are shown in Figure 13. For routine purposes the phages corresponding to rare Vi-types are pooled so that the test may be completed on one plate. Full details of the media, techniques, and methods of reading. Figure 13. Reactions of S. typhi to its typing phages. Left, right, Vi-t ype J. Vi-tv pe and interpretation are given by Anderson and Williams (1956). 4. Theoretical Aspects of Vi-Phage Typing a. The Adaptation of Vi-Phage II All the adapted typing preparation
. Bacteriophages. Bacteriophages; Bacteriophages. USE OF PHAGES IN EPIDEMIOLOGICAL STUDIES 405 typical typhoid phage typing plates are shown in Figure 13. For routine purposes the phages corresponding to rare Vi-types are pooled so that the test may be completed on one plate. Full details of the media, techniques, and methods of reading. Figure 13. Reactions of S. typhi to its typing phages. Left, right, Vi-t ype J. Vi-tv pe and interpretation are given by Anderson and Williams (1956). 4. Theoretical Aspects of Vi-Phage Typing a. The Adaptation of Vi-Phage II All the adapted typing preparations of Vi-phage II are neutralized by an antiserum against phage A, which was the form in which the phage was first isolated, and there is no doubt that all are modifications of the one phage. The demonstration of the variability of host range of Vi-phage II stimulated con- siderable interest in the possible mechanism of adaptation, and also aroused curiosity concerning the nature of the differences between the various Vi-types of the typhoid bacillus. Craigie and Yen (1938) believed that a specific host-range mutant of Vi- phage II existed for each Vi-type of Salmonella typhi, and suggested that the process of phage "adaptation" consisted in the selection. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Adams, Mark Hancock, 1912-1956. New York, Interscience Publishers
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