. Hospital Gazette and Archives of Clinical Surgery . Plate No. i. Histology.—The histological processes in Rosacea are probablythe same as occur in chronic congestive and inflammatory states else- ACNE ROSACEA OUTGROWTHS REMOVED. 2:j where. In the third stage, which alone I have had an opportunity ofexamining microscopically, I have found great thickening of the cori-um with development of new connective tissue and enlargement ofthe blood-vessels, principally the veins. The sebaceous glands weremany of them enlarged, sharing with the other elements of the skinthe common hypertrophic tendencie
. Hospital Gazette and Archives of Clinical Surgery . Plate No. i. Histology.—The histological processes in Rosacea are probablythe same as occur in chronic congestive and inflammatory states else- ACNE ROSACEA OUTGROWTHS REMOVED. 2:j where. In the third stage, which alone I have had an opportunity ofexamining microscopically, I have found great thickening of the cori-um with development of new connective tissue and enlargement ofthe blood-vessels, principally the veins. The sebaceous glands weremany of them enlarged, sharing with the other elements of the skinthe common hypertrophic tendencies. They did not appear, how-ever, to have undergone any qualitative changes, with the exceptionthat some of them were filled with impacted sebum. Small cell. Tlaie Xo. 2. infiltration occurred to a limited extent along the course of thevessels. In a specimen from a case of excessive enlargeme-nt referred to meby Dr. C. Wagner for microscopical examination, in which the por-tions removed weighed about four hundred and forty grains, I foundthe following changes: The stratum corneum was exceedingly scant,consisting at most of but one or two layers, and in some parts entirelyabsent. The stratum Malpighii was very thick, with mostly large and 24 CLINTON WAGNER. woll formed cells. In some parts, however, the nuclei were shrunkenand deformed, or entirely absent, leaving vacuoles. lhe pai)ill;\) wereenlarged in lengtli and breadth, and contained many round and fusi-form cells. The sebaceous glands were not much altered except thatthe nuclei of the cells were indistinct, and did not imbibe carminereadily. In many cases the nuclei were shriveled or absent. Themargins of the cells were irregular. Some of the glands were normal,but the others were und
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