Organic and functional nervous diseases; a text-book of neurology . e medulla oblongata, occupying the column of Gollor the median portion of the column of Burdach. An attempt is madein Figs. 22 and 23 (page 69) to demonstrate this distribution of the PATHOLOOY. 345 Various fibres entering at different levels. (See also Plate IX., p. 52.)All these fibres are degenerated in locomotor ataxia. The extent ofthe degeneration in the spinal cord will depend entirely upon the severityof the disease and upon the number of posterior nerve roots which areinvolved in the affection. In the early stage of l
Organic and functional nervous diseases; a text-book of neurology . e medulla oblongata, occupying the column of Gollor the median portion of the column of Burdach. An attempt is madein Figs. 22 and 23 (page 69) to demonstrate this distribution of the PATHOLOOY. 345 Various fibres entering at different levels. (See also Plate IX., p. 52.)All these fibres are degenerated in locomotor ataxia. The extent ofthe degeneration in the spinal cord will depend entirely upon the severityof the disease and upon the number of posterior nerve roots which areinvolved in the affection. In the early stage of locomotor ataxia, when but few fibres aredegenerated, the region of sclerosis is extremely limited in extent. Asthe disease begins in the vast majority of cases in the neurones of thelumbar nerves, it is in the lumbar segments only of the cord that thelesion is evident, though, inasmuch as these lumbar nerves send somefibres all the way up to the medulla, an examination will show someaffection of every segment of the spinal cord at the area through which Fig. First lumbar segment of the cord in locomotor ataxia in the early stage of the disease. The sclerosis Ismore evident on the right side in the root zone of the column of Burdach. they pass. Figs. 149 and 150 demonstrate the distribution of thelesion in early cases of tabes where the lesion was thus limited to thelumbar enlargement. As the disease advances, a larger number of ganglia and posteriornerve roots are involved, and a greater extent of tissue is degeneratedin the posterior columns. The series of sections (Figs. 152 to 154)demonstrate the lesions of tabes. The original lesion has destroyedthe posterior columns in the lumbar region and has extended throughthe dorsal region, and involved the cervical region of the cord. Thesefigures show a series of sections at various levels from a patient who suf-fered thirty years from the disease, and whose symptoms were as markedin the upper extremities as in the lower. In a
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