Collected papers . 0096 0 27 0,0096 s 98 0,065 s 98 0,065 0 98 0,065 0 87 0,06 0 80 0,13 s 69 0,065 s 69 0,065 0 69 0,065 0 69 0,065 0 69 0,065 0 69 0,065 sis 69 0,065 0 69 0,065 0 69 0,065 s 69 0,065 0 IVo 0,129 0 IA 0,129 0 32 0,129 s 32 0,065 s 32 0,065 s 32 0,065 s 32 0,065 s 12 0,065 0 13 0,065 0 13 0,065 0,036 X0,048 X0,048 X0,06 X0,06 X0,090,0460,046 0,065 0,0650,065 It will be seen from the table that in a number of in-stances the occurrence of symptoms after the second injectiondid not interfere with the hypersensibility and that death orsevere symptoms resulted when the egg albumin w
Collected papers . 0096 0 27 0,0096 s 98 0,065 s 98 0,065 0 98 0,065 0 87 0,06 0 80 0,13 s 69 0,065 s 69 0,065 0 69 0,065 0 69 0,065 0 69 0,065 0 69 0,065 sis 69 0,065 0 69 0,065 0 69 0,065 s 69 0,065 0 IVo 0,129 0 IA 0,129 0 32 0,129 s 32 0,065 s 32 0,065 s 32 0,065 s 32 0,065 s 12 0,065 0 13 0,065 0 13 0,065 0,036 X0,048 X0,048 X0,06 X0,06 X0,090,0460,046 0,065 0,0650,065 It will be seen from the table that in a number of in-stances the occurrence of symptoms after the second injectiondid not interfere with the hypersensibility and that death orsevere symptoms resulted when the egg albumin was injectedafter a sufficient interval for a third tinxe (vide Nos 25, 34,35, 37, 38, 39, 53, 54, 58, 59, 64, 67, 73, 74, 75). A closeconsideration of the table will reveal that while the hyper-sensibility is not necessarily destroyed by the second doseproductive of symptoms, this depends to some extent on themanner of preparation. It must be pointed out in this place. sis Hypersensibility to pure egg albumin. 711). that by symptoms is meant paralysis, convulsions and moreor less complete unconsciousness. By slight symptoms ismeant either convulsions without paralysis or dyspnoea, paresisand inability of sitting or standing. No less marked symptomswere regarded as evidence of hypersensibility, although itcould be shown that intraperitoneal injections frequentlyyielded a negative result, while intracardiac injections causedparalysis or death. It would seem that the sudden fall intemperature during the shock might be a good indication ofhypersensibility, as suggested by H. Pfeiffer and S. Mita 720 H- W. Armit, (1909), but unless confirmed by some other symptoms, a merefall of temperature must not be regarded as conclusive proofof the hypersensibility, and further when distinct symptomsof hypersensibility to the special protein employed are seen,the absence of a fall in temperature cannot be regarded asof any diagnostic importance. When the preparatory dose ofserum was a large one
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