. Pathological technique; a practical manual for workers in pathological histology and bacteriology. Fig. 115.—Sporotrichum Schenckii. Colonies on glycerin-agar plate. Lowpower (L. Hektoen and C. F. Perkins). Pathogenesis.—The micro-organism is pathogenic for ex-perimental animals, especially for white rats. In the latter PATHOGENIC BACTERIA AND FUNGI. 375 animals, septicemia, and disseminated suppurative or granu-lomatous lesions may be produced by inoculation with cul-tures. The testicles are very frequently involved after 1 Fig. 116.—Sporotrichum Schenckii. Margin of hanging-drop culture ;


. Pathological technique; a practical manual for workers in pathological histology and bacteriology. Fig. 115.—Sporotrichum Schenckii. Colonies on glycerin-agar plate. Lowpower (L. Hektoen and C. F. Perkins). Pathogenesis.—The micro-organism is pathogenic for ex-perimental animals, especially for white rats. In the latter PATHOGENIC BACTERIA AND FUNGI. 375 animals, septicemia, and disseminated suppurative or granu-lomatous lesions may be produced by inoculation with cul-tures. The testicles are very frequently involved after 1 Fig. 116.—Sporotrichum Schenckii. Margin of hanging-drop culture ; X about150 (L. Hektoen and C. F. Perkins).. Fig. 117.—Sporotrichum Schenckii. Margin of hanging-drop culture ; X about1000 (L. Hektoen and C. F. Perkins). intraperitoneal inoculation. In the experimental lesions theorganism does not appear in the filamentous form, but onlyin modified forms, more or less resembling the spores and 376 PATHOLOGICAL TECHNIQUE. as oblong Gram-staining bodies, I to 3 microns wide and 10to 12 microns long. Sometimes small bud-like processesproject from these forms. Occurrence.—The fungus is thought to have a naturalhabitat in the outer world and to be widely distributed. Itis claimed that spontaneous infection with it has been ob-served in the dog and rat, and that some of the cases ofepizootic or mycotic lymphangitis in horses are due to infec-tion with it. Diagnosis.—The only practical way by which Sporo-trichum Schenckii may be recognized in suspected sporo-trichosis is by obtaining it in cultures from unopened gum-mata or abscesses. As has been pointed out above, it ispractically impossible


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