. Carnegie Institution of Washington publication. STRUCTURAL CHANGES IN THE POISON GLAND. 31 (C2) Gland 10 Minutes after Injection of Pilocarpine. Sections showed the granules still present in a considerable number of cells, but the latter were less numerous than in the unstimulated gland. The number of granules in each cell was also less. The lumen of the tubules con- tained an abundant granular mass. Experiment III. An animal (D) was injected with grain of pilocarpine and, after an in- terval of 24 hours, pieces of the gland were removed and fixed in Kopsch fluid. Examination of the sect
. Carnegie Institution of Washington publication. STRUCTURAL CHANGES IN THE POISON GLAND. 31 (C2) Gland 10 Minutes after Injection of Pilocarpine. Sections showed the granules still present in a considerable number of cells, but the latter were less numerous than in the unstimulated gland. The number of granules in each cell was also less. The lumen of the tubules con- tained an abundant granular mass. Experiment III. An animal (D) was injected with grain of pilocarpine and, after an in- terval of 24 hours, pieces of the gland were removed and fixed in Kopsch fluid. Examination of the sections indicated that the gland had almost regained its normal activity. Some of the lobules were apparently perfectly normal, the Wmm m -. .,..>'. -lite Sim SIM mSm IS* Fig. 13.—Two thin sections of intralobular tubules of a gland 24 hours after injection of pilocarpine. Some cells show initial steps in granule formation (Zeiss oc. 4, obj. 3 mm., ap. ). number of granule-containing cells being nearly if not quite as numerous as in similar lobules of the normal gland. In other lobules the number of such cells was much less and in many instances they contained only a few granules. In many cells the granules were apparently in the process of formation, appear- ing as minute particles at the intersections of the cytoplasmic network. Fig. 13 represents a section passing through two intralobular tubules. The greater number of cells, it will be observed, are filled with a relatively dense cytoplasm similar to that which in normal granule-containing cells forms a basal layer (cf. fig. 10). In other cases the cytoplasm is more clearly alveolar. In these cells granules are usually present, in some cases in early stages of formation, in others almost fully Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original work.
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