. The endocrine organs; an introduction to the study of internal secretion . A B FIG. 22.—A case of endemic goitre (A) before and (B) after treatmentwith thyroid, (v. Brun.) by symptoms of hypothyroidism; not, as might have been expected, bythose of when the enlargementis the result of malignantcell-proliferation (carci-noma or sarcoma), the func-tions of the organ may stillbe carried on. It is indeeda significant fact in con-nexion with the genesis ofmalignant tumours, thatwhen in such cases thewhole of the thyroid isremoved by the surgeon,should there be any meta-static g
. The endocrine organs; an introduction to the study of internal secretion . A B FIG. 22.—A case of endemic goitre (A) before and (B) after treatmentwith thyroid, (v. Brun.) by symptoms of hypothyroidism; not, as might have been expected, bythose of when the enlargementis the result of malignantcell-proliferation (carci-noma or sarcoma), the func-tions of the organ may stillbe carried on. It is indeeda significant fact in con-nexion with the genesis ofmalignant tumours, thatwhen in such cases thewhole of the thyroid isremoved by the surgeon,should there be any meta-static growths elsewhere, in the liver, the usualsymptoms of cachexiastrumipriva do not showthemselves. The enlargement of thegland in endemic goitregenerally takes the formof a diffuse hypertrophy: the follicles enlarge and their epithelium pro-liferates : new follicles may also become formed. There is nearly always a 3
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