Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . tumand eyelids, and of thelips, alae of the nose andears; in the connectivetissue between the mus-cle-fibers (pseudohyper-trophic muscular paral-ysis, Fig. 133); in thesubserous structures; andin other connectivetissues. A more or lesscircumscribed collectionof fat constitutes a neo-plasm known as a lipoma(see Tumors). The gen-eral infiltration of fat intoan organ—such, for ex-ample, as the jheart—isreferred to as lipomatosis,or adiposis, of the tissueinvolved. When the in-filtration
Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . tumand eyelids, and of thelips, alae of the nose andears; in the connectivetissue between the mus-cle-fibers (pseudohyper-trophic muscular paral-ysis, Fig. 133); in thesubserous structures; andin other connectivetissues. A more or lesscircumscribed collectionof fat constitutes a neo-plasm known as a lipoma(see Tumors). The gen-eral infiltration of fat intoan organ—such, for ex-ample, as the jheart—isreferred to as lipomatosis,or adiposis, of the tissueinvolved. When the in-filtration of fat is exten-sive, constituting whatmight be termed a universal lipomatosis, the condition is commonlyspoken of as obesity or adiposity. Dercum first described a peculiarform of general lipomatosis associated with pain and other nervousphenomena, and the condition is now generally known as Dercumsdisease. At first the fat deposits appear to be limited, but later maybecome extensive. The affected areas are tender and there is tender-ness over the nerve-trunks. Some of the muscles inav give the reac-. mi^^i ^s- V Fig. 132.—Heart, Extreme Fatty Endocardium. B. Vein in myocardium. C. Epicardium. fat. E. Irregularly distributed through the myo-cardium from just above the leader from B nearly to C are col-umns of fat as shown at E. F. The infiltrating fat separates themuscle into irregular bands such as may be seen at i^.but becomingthinner above and thicker below this point. AND DEC. K\ KR Muv le-rilx Innitralcl\ fat. tions of degeneration. In coiisidrralion of tin- tenderness an«l proposed the name adiposis dolorosa. Microscopically, in the subcutaneous and areolar structures, thefat is taken up by the connective-tissue cell; the nucleus is crowded toone side, the fat existing in the cellas a single large oil-globule; in theliver the fat is stored in the hepaticcell. The nuclei of the infiltrated cellsare n
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