. A text-book of practical therapeutics, with especial reference to the application of remedial measures to disease and their employment upon a rational basis . vulsions, and if artificialrespiration is not used the animal diesfrom failure of respiration. If death A nux vomica motor tafces place frQm fae effects of the drug, tracts in the spinal cord and to a slight .-. L , P i , i i extent the nerve-trunks; b, in large, the motor nerves are found to be de-poisonous doses it depresses the motor pressed, partly as the result of the poison- nerve-plate in the muscle and exhausts Q
. A text-book of practical therapeutics, with especial reference to the application of remedial measures to disease and their employment upon a rational basis . vulsions, and if artificialrespiration is not used the animal diesfrom failure of respiration. If death A nux vomica motor tafces place frQm fae effects of the drug, tracts in the spinal cord and to a slight .-. L , P i , i i extent the nerve-trunks; b, in large, the motor nerves are found to be de-poisonous doses it depresses the motor pressed, partly as the result of the poison- nerve-plate in the muscle and exhausts QUS ^ f ^ strychnine, and partly the nerve-trunks. J . r J as the result of the exhaustion of thenerve-trunks by the convulsing impulses which they have carried(Fig. 51). Circulation.—Nux vomica increases the force of the pulse-beatand the pulse-rate by a stimulation of the heart-muscle and its ganglia,while the rise of arterial pressure which it causes is due to stimulationof the vasomotor centre. If very poisonous doses are injected intra-venously, a fall of arterial pressure occurs instead of a rise, which isdue to vasomotor depression and NUX VOMICA. 353 Respiration.—Strychnine is one of the most constant and powerfulstimulants of the respiratory centre that we have, and it not onlyincreases the rate, but also the respiratory capacity. Temperature.—Ordinary doses have no effect upon temperature,but poisonous doses may raise it by reason of the convulsions. Elimination.—Strychnine is eliminated from the body by the kid-neys as strychnine and strychnic acid. Most of it is oxidized anddestroyed by the liver. Therapeutics.—Nux vomica, or its chief alkaloid strychnine, is usedfor several purposes in medicine. Owing to its bitter character, itmay be employed as a simple bitter tonic or as one especially influencingthe nervous system. It may also be used as a respiratory, cardiac,and ocular stimulant. In cases of junctional nervous atony, or depression, strych
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