Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . ygranular and bacilli can be demon-strated in the vessels and tufts. Herzog describes and figures thepresence of hyaline thrombi in the renal glomeruli. The liver isfre(]uently slightly enlarged and may contain areas of observed marked swelling, necrosis, and hemorrhage in thesolitary and agminated follicles of the intestine, hemorrhages in themucosa, and enlarged mesenteric glands often containing necrotic andhemorrhagic foci. The brain and spinal cord are sometimes co
Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . ygranular and bacilli can be demon-strated in the vessels and tufts. Herzog describes and figures thepresence of hyaline thrombi in the renal glomeruli. The liver isfre(]uently slightly enlarged and may contain areas of observed marked swelling, necrosis, and hemorrhage in thesolitary and agminated follicles of the intestine, hemorrhages in themucosa, and enlarged mesenteric glands often containing necrotic andhemorrhagic foci. The brain and spinal cord are sometimes congestedand in rare instances fibrinous meningitis and meningoencephalitis havebeen observed. Congestion, proliferative processes, and necrotic lesion.^occur in the bone-marrow. An antitoxin may be prepared by the repeated intravenous injectionof slowlv increasing doses of pest bacilli until the animal acquires amarked immunity; the horse is usually used. In beginning the processof immunization it may be well to employ killed cultures, followed laterby living bacilli. The value of plague Fig. 75.—Sectiov of Kidney Showing Malpig-HiAN Body Costaintno Pest Baolu. in Koa solution, embed led in pamffin;ind slainc<l in corboltuluidin blue and dificr-entiated by glyccrin-cther. ZeiM b cvc-picfcand 1] inch homogeneous oil-immersion ob-jective. a. Capsule of Bowman, h. EpIcapsule, some of which (f)«/, d. Capillaries in glomeniliwhich (f. c. e, c) are many lili. h.« II n 1 ti irm 1 132 PATHOLOGY. Haffkines protective inoculation is undoubtedly of very great fluid used is prepared from cultures of the bacillus in bouillon, thesurface pellicle being allowed to develop as often and fully as bacilli are killed by exposure to 65° C. for one hour and per cent,carbolic acid added. From 5 to 10 of this fluid, depending uponits strength, is injected subcutaneously. The maximum protectionappears durin
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