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The Journal of laboratory and clinical medicine . hose solubility resembles that of silver cyanide. The substance itself freed frompicrolonic acid is practically neutral in reaction, \tvy soluble in water and al-cohol, somewhat soluble in ether. It gives a picrolonate in the form of very fine RECORD B. (See opposite page.) (Dog 2)Injection given by femoral —5 mgms. of synthetic substance per kilo body weight. Fall in pressure from first injection about 25 mm. Hg. Fall in pressure from second injection about 10 mm. Hg. Interval between injection 1 and injection 2 about 50
The Journal of laboratory and clinical medicine . hose solubility resembles that of silver cyanide. The substance itself freed frompicrolonic acid is practically neutral in reaction, \tvy soluble in water and al-cohol, somewhat soluble in ether. It gives a picrolonate in the form of very fine RECORD B. (See opposite page.) (Dog 2)Injection given by femoral —5 mgms. of synthetic substance per kilo body weight. Fall in pressure from first injection about 25 mm. Hg. Fall in pressure from second injection about 10 mm. Hg. Interval between injection 1 and injection 2 about 50 seconds. Interval between recovery from first injection and administration of second, about 20 seconds. Note: The heart rate cannot be estimated 1 ecause while taking the tracing, the recording pointerof the chronograph fell off. After the tracing was finished, we attempted to svipply a time record, but itdid not prove to be synchronous with the former rate of movement of the drum, which was running time record is therefore 308 The Journal of Laboratory and Clinical Medicine microscopic needles which melt at a 118° C, solidifying rapidly to an orange-colored mass which melts with decomposition at about 230° C. gms. aresoluble in 100 of hot water. Upon analysis it gives the following percentage composition, gms. substance gives 26 N. at 24°C. and 746 gms. give gms. CO, and gms. Found N Calculated for (C,H,N,) (QoH3N,0,) The substance agrees in percentage comi)osition with the picrolonate ofmethylcyanamide. Methylcyanamide was prepared synthetically from methylmustard oil. It resembles the naturally occurring substance both in reactionand solubilities. Its picrolonate was prepared and found to melt at 116° C. so-lidifying immediately to an orange-colored mass which melted at 230° C. with de-composition. In this respect the picrolonate agrees in its behavior with thepic
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Keywords: ., bookcentury1900, bookdecade1910, booksubject, booksubjectmedicine