Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . ring the secondary period, we ^ See Gaz. Hebd. de Med. et de Chir., 1902, Nos. i and 2, p i. ^ See second foot-note, p. 472: also Schupfer, Rif. Med., March 2, IQ04. 3 Erdmann, Deut. Arch. f. klin. Med., 1902, Bd. Ixxiv, H. 5 and 6. ^Stock-ton, Jour. Amer. Med. Assoc, Nov. 8, 1902, p. 1167. Boix, Arch Gen. deMed., Paris, 1903, vol. Ixxx, Nos. 19, 20. 50 possess but little aerurate kiiowled.^e. The fact tliat jaundice andhepatic enlaru;einent occur, and that hiter cirrhosis may


Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . ring the secondary period, we ^ See Gaz. Hebd. de Med. et de Chir., 1902, Nos. i and 2, p i. ^ See second foot-note, p. 472: also Schupfer, Rif. Med., March 2, IQ04. 3 Erdmann, Deut. Arch. f. klin. Med., 1902, Bd. Ixxiv, H. 5 and 6. ^Stock-ton, Jour. Amer. Med. Assoc, Nov. 8, 1902, p. 1167. Boix, Arch Gen. deMed., Paris, 1903, vol. Ixxx, Nos. 19, 20. 50 possess but little aerurate kiiowled.^e. The fact tliat jaundice andhepatic enlaru;einent occur, and that hiter cirrhosis may develop, indi-cates the possibility of an acute difYuse interstitial hepatitis and catar-rhal cholani^ntis. Later syphilitic infection i^ives rise to definite ^ummata(p. i7q). These may occupy the interior of the origan, ytresent on thesurface as delinite bosses, or rarely as semi])edunculated masses. Themargin of the gumma is not sharply defined, and, as Hirch-IIirschfeldobserves, the mass can seldom be shelled out of the hepatic tissue;even in the pedunculated syphilomata liver tissue is present in the. FiC. 368.—LSDtR StRFACK OF I-IVKR Slli>\VlSr. ResVLTS OF CONGENITAL S\TliaiS. .1, .1. Gall-bladder. B. Round liRamont. The orKan is irregularly fissured in many directions, riviiik n>c toa larRc numlHT of IoIh-s. Ilie iKilient from whom this liver was removed dietl in the second week of typhoidfever; age, seventeen years. pedicles and partly incloses the nodule. Scars from healed gummatamay sometimes be observed. It is well known that syphilitics are sub-ject to amyloid disease, and that this afTection commonly involves theliver (p. 227). Tuberculosis of the Liver.—Pulmonary tuberculosis is often accom-panied by fatty infiltration of the liver, with which, or independently,a ])eriportal cirrhosis sometimes occurs. It is known that the poison Moussct and Bonainour, Rev. de .MOd., April. TQ04. Vincer;^> • RifMed., Nov. 16, 1904. Giordano, Rif. Med., Nov. 46. 1904


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