. A manual of poisonous plants, chiefly of eastern North America, with brief notes on economic and medicinal plants, and numerous illustrations. Poisonous plants. SCHIZOPHYTAâSCHIZOAIYCETES 181 Animals immune. Laboratory animals. Pathogenesis. The organism is found present in leprous tissues, almost filling the cells in many instances. Several types of leprosy are differentiated. -m-^.. '^â r -,l?<-^? Fig. tissue. 30h. Glanders bacillus, a. Section through "glandereal" the small rods massed or single, h. Bacilli stained with methyl-blue. After Fliigge. on the basis of the organ or


. A manual of poisonous plants, chiefly of eastern North America, with brief notes on economic and medicinal plants, and numerous illustrations. Poisonous plants. SCHIZOPHYTAâSCHIZOAIYCETES 181 Animals immune. Laboratory animals. Pathogenesis. The organism is found present in leprous tissues, almost filling the cells in many instances. Several types of leprosy are differentiated. -m-^.. '^â r -,l?<-^? Fig. tissue. 30h. Glanders bacillus, a. Section through "glandereal" the small rods massed or single, h. Bacilli stained with methyl-blue. After Fliigge. on the basis of the organ or tissues in the body infected. In many of its- aspects, the disease resembles tuberculosis. Poisonous properties. The organism has not been successfully cultivated^ Poisons are unknown. Immunity. Bacterium pesiis, Lehmann-Neumann Disease produced. Bubonic plague. Animals infected. Man. Animals susceptible. Rat, guinea pig, monkey. Pathogenesis. Infection usually cutaneous. The lymph glands become swollen, and hemorrhagic and undergo more or less extensive necrosis, gen- eralized septiceimia in many cases, pneumonia and hemorrhages in various mucous membranes, especially in the stomach and endothelial surfaces, such as. the pericardium and in various parenchymatous organs, with extreme degenera- tion of the latter. Spleen swollen. Poisonous properties. The toxic substance is obscure. The filtrates from young cultures usually show little, or no toxicity; the older, more. The toxic substance seems to be susceptible to heat and is present in cultures killed by chloroform. Immunity. Immunity may be conferred by the injection of sterilized or attenuated cultures, and this vaccination is practiced in some Asiatic countries. Microspira comma, Schroeter Disease produced. Asiatic cholera. Animals infected. Man. Animals susceptible. Laboratory animals naturally are immune to the disease, but by preventing peristalsis, and neutralizing the acid gastric juice, some experimenters have succ


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