. The American journal of roentgenology, radium therapy and nuclear medicine . d previouslyoccupied the hemispheres giving rise to anedematous condition of the treated side. The first proposition is responsible forthis increase in dry weight only in a verysmall degree, if at all, because histologicalstudy shows no such extensive cellularinfiltration or proliferation. In attempting to prove or disprove thesecond idea, the total nitrogen of the nitrogen. The difference in the two analysedhemispheres was ~5 gm. of nitrogen. Thediscrepancy of gm. is within the limitof error of the experim
. The American journal of roentgenology, radium therapy and nuclear medicine . d previouslyoccupied the hemispheres giving rise to anedematous condition of the treated side. The first proposition is responsible forthis increase in dry weight only in a verysmall degree, if at all, because histologicalstudy shows no such extensive cellularinfiltration or proliferation. In attempting to prove or disprove thesecond idea, the total nitrogen of the nitrogen. The difference in the two analysedhemispheres was ~5 gm. of nitrogen. Thediscrepancy of gm. is within the limitof error of the experiment. Hence we are inclined to assume thatthe observed increase in the weight of thetreated hemisphere can be accounted forentirely by an existing edema. We have already noted the fact that anexposure of greater than 1,400 mgm. hourswas followed by death, with a single excep-tion (dog 20). With this single exceptionthe animals have responded so uniformlythat the results follow, when plotted withdoses in mgm. hours as abscissae, andlength of life after operation as ordinates,. Fig. 1 mgm. hrs. Fig. 2. mgm. hrs. treated and untreated hemispheres ofdog 27 was determined by the method The increase of the total nitrogenon the treated side is sufficient to disprovethe second theory. This difference, however, is not incon-sistent with the third view, but, on theother hand, rather supports it. For itwe assume that the difference in weight ofthe two hemispheres, gms., is due toedema—distention of the lymph spacesand flooding of the tissues with a lymph-like fluid—we can come to the followingconclusion: We know that lymph containsapproximately 5 per cent protein, there-fore in an increase of gm., have been due to protein would contain gm. nitrogen,since gm. protein contain 1 gm. of almost a straight line (Fig. 1). In fact,following this graph, it was possible topredict within one or two days the timeof death of an animal.
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