. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . Fig. 58a.—Photograph of the ovum with the piece to which the vesicleis attached cut out and turned over. with the abortion of the ovum. The time between the begin-ning of the last period and the abortion is 71 days. Cohabi-tation July 25 to August 5 and again on August 15, or sev-eral days before the first lapsed period. The ovum is only partly covered with villi and is filled witha jelly-like mass of magma. Floating within this mass there No. I.] ORIGIN OF HUMA


. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . Fig. 58a.—Photograph of the ovum with the piece to which the vesicleis attached cut out and turned over. with the abortion of the ovum. The time between the begin-ning of the last period and the abortion is 71 days. Cohabi-tation July 25 to August 5 and again on August 15, or sev-eral days before the first lapsed period. The ovum is only partly covered with villi and is filled witha jelly-like mass of magma. Floating within this mass there No. I.] ORIGIN OF HUMAN MONSTERS. 165 is a large vesicle, 6 mm. in diameter, with transparent vesicle in turn is partly filled with a granular deposit. The syncytium is excessive. The mesoderm of chorion andinclosed vesicle is very fibrous. There are blood islands and. Fig. 58b. Fig. 58c Fig. 58b.—Sections through the vesicle at its attachment on the 10 times. Within the stem there is a sharply defined cavity linedwith epithelium and an hour-glass-like space filled with blood. Onone side the stem is covered with epithelium. Fig. 58c.—The cavity of the stem, shown in Fig. 58b, enlarged 50 times. a cavity lined with epithelium in the stem of the vesicle. Themain portion of the vesicle is composed of two layers, butnear the stem there are three layers present. The mesodermof the villi is hyaline and cedematous, and between them thereis a stringy mass of mucus or fibrin rich in leucocytes. i66 MALL. [Vol. XIX. No. 60. Embryo, C. R., 8 mm. Dr. Dobbin, Baltimore. The body and extremities of the embryo appear normal inform. The tissues are considerably macerated and may benormal. The spinal cord is solid. There are large islands ofblood cells in the liver. No. 69. Ovum, 70 x 40 x 30 mm.; embryo, C. R., 13. Dr. Chabot, Baltimore. The chorion i


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