. Special pathology and therapeutics of the diseases of domestic animals. Veterinary medicine. 954 Osteomalacia. Pathogenesis. The commencement of the pathological IDrocess in the bones is probably similar to that in rachitis (see p. 937), whether the trouble l)e dne to a lime deficiency of the organism or to another cause. But since in this disease the process occurs in fully developed bones, the later tissue changes differ more or less from those in rachitis. In osteo- malacia the peculiar proliferative processes are absent which are noted in rachitis at the borders between the epiphyses and
. Special pathology and therapeutics of the diseases of domestic animals. Veterinary medicine. 954 Osteomalacia. Pathogenesis. The commencement of the pathological IDrocess in the bones is probably similar to that in rachitis (see p. 937), whether the trouble l)e dne to a lime deficiency of the organism or to another cause. But since in this disease the process occurs in fully developed bones, the later tissue changes differ more or less from those in rachitis. In osteo- malacia the peculiar proliferative processes are absent which are noted in rachitis at the borders between the epiphyses and the diapliyses of the long bones, and on the other hand the decalcification (osteoporosis) predominates over the new- formation of osteoid tissue, at least in many cases. Still, ex- ceptions are observed not very infrequentl}^, in so far as a decided proliferative process may set in under the influence of certain mechanical factors (see p. 937) and of other agencies. Fig. 165. Skeleton of the cow witli osteomalaria, illustrated in Fig. 168. The ribs are bent forward, show nmltijile fractures, and callus formation. Both ilia are fractured, tlie fractured ends lieing crowded into one another. Enormous callus for- mation, moderate lordosis of the lumbar vertebrae ; callus formation at the base of the spinal ]jrocesses of the anterior dorsal vertebrae. that are not fully known. In other cases the new-formation of osteoid tissue may be entirely lacking. The further consequences of the diminution in the firmness of the bones and of the disturbances in the metabolism are the same as in rachitis (see p. 937), except that in osteomalacia the bones are more often brittle ratlier than pliable. Relations of Rachitis to Osteomalacia. While Virchow and others differentiated rachitis sharply from osteomalacia, still other authors declared ])oth diseases to he closely related, or identical. Indeed the pathogenesis and the etiological agencies of hgth affections agree in many points, and it ap
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