. The Journal of nervous and mental disease. sal corner of the globus, in the angleincluded between the lateral lamina and the internal capsule, the pale,fine, yellowish fibers, which pass between globus and caudate nucleus,are abundant. At this level the proliferated neuroglia occupies anarea extending about two thirds of the way across the putamen fromthe external capsule; dorsally it has slightly encroached upon someof the bridges of gray matter between the fibers of the internal cap- KM /.. NEWMARK aced into the globus pallidas at about its middle third, reckoningsule, and ventrally it has


. The Journal of nervous and mental disease. sal corner of the globus, in the angleincluded between the lateral lamina and the internal capsule, the pale,fine, yellowish fibers, which pass between globus and caudate nucleus,are abundant. At this level the proliferated neuroglia occupies anarea extending about two thirds of the way across the putamen fromthe external capsule; dorsally it has slightly encroached upon someof the bridges of gray matter between the fibers of the internal cap- KM /.. NEWMARK aced into the globus pallidas at about its middle third, reckoningsule, and ventrally it has extended not quite to the base of the puta-men. Thus far the naked eye perceives in tin- Weigert sections inthe lenticular nucleus nothing more than the shrinking of the puta-men. the contraction of which has been almost exclusively in itswidth, and the slightly smaller size of the right globus bundles of fibers can be seen directed toward- the externallamina, and the substance of the putamen has not undergone Fig. 5. Cavitation in right putamen. But about the level of the genu of the internal capsule, at the an-terior extremity of the optic thalamus, where the globus pallidus hastwo distinct zones, and where the lenticular ansa appears (Figs. 5and 6), the pathological process in the putamen becomes more in-tense. Xot only are the perivascular spaces larger than hitherto, butlarge spaces have formed through almost the whole vertical extentof the putamen, in consequence of the breaking down, or tearing, ofthe neuroglia, and of the opening of the spaces thus formed into thelarge ones around the blood vessels. Around a vessel at the base ofthe putamen there is a large ma<< of lymphocytes, but within theputamen it-elf lymphocytes do not appear in considerable numbers LESION IN THE PUT AMEN 105 which might indicate a special affection of this region by the vessels within the affected area are not conspicuously diseased,although some


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Keywords: ., bookcentury1800, bookdecade1870, booksubjectpsychologypathologic