. The thyroid gland in health and disease. m is rapid. This is especiallynotable in the case of tetanus, B. mallei, and anthrax (Farrant).Of toxic substances affecting the gland other than the productsof bacteria the most important are those produced by helminthsin the bowel. Bcdson has shown that the mashed-up bodies of theseworms when injected into animals in small doses over long periodsinduce a condition of hyperplasia of the thyroid. In larger dosesthe hyperplasia eventually gives place to fibrosis, wluch then TOXIC PRODUCTS OF INTESTINAL ORGANISMS 45 becomes a notable feature of the glan
. The thyroid gland in health and disease. m is rapid. This is especiallynotable in the case of tetanus, B. mallei, and anthrax (Farrant).Of toxic substances affecting the gland other than the productsof bacteria the most important are those produced by helminthsin the bowel. Bcdson has shown that the mashed-up bodies of theseworms when injected into animals in small doses over long periodsinduce a condition of hyperplasia of the thyroid. In larger dosesthe hyperplasia eventually gives place to fibrosis, wluch then TOXIC PRODUCTS OF INTESTINAL ORGANISMS 45 becomes a notable feature of the gland. An even more im-portant observation by Bedson is the fact that such toxic productsof worms have a still more pronounced action on the fact that these organs, which are an integral part of thesympathetic system and intimately interact with the thyroid,are stimulated by the toxic derivatives of intestinal parasites,is an etiological observation of high importance. No better illustration of the action of the toxic products of. 4
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