. The endocrine organs; an introduction to the study of internal secretion . idue extracted with Locke; the remainder of thegland which was left after the chloroform and alcohol had acted upon it being alsoextracted with Locke. A striking effect of intravenous injection is obtained with extracts ofhilum (interstitial cells). This usually causes inhibition of the normalrhythmic movements, if present, and diminution of tone of the uterinemuscle, which may be preceded by an increase (fig. 96). Accompanyingthis change there is a considerable fall in blood-pressure, even in atropinisedanimals, and
. The endocrine organs; an introduction to the study of internal secretion . idue extracted with Locke; the remainder of thegland which was left after the chloroform and alcohol had acted upon it being alsoextracted with Locke. A striking effect of intravenous injection is obtained with extracts ofhilum (interstitial cells). This usually causes inhibition of the normalrhythmic movements, if present, and diminution of tone of the uterinemuscle, which may be preceded by an increase (fig. 96). Accompanyingthis change there is a considerable fall in blood-pressure, even in atropinisedanimals, and a diminution in volume of the kidney. Corpus luteum extractinjected into the veins causes the uterus if quiescent to begin contracting, ifalready contracting to increase its contractions and to assume an increasedtone. Little or no effect on blood-pressure or kidney volume is producedby this extract. The result of immersing portions of uterus or strips of uterine andmost other plain muscle in extract of follicular tissue or liquor folliculi is 141 142 The Endocrine Organs. oa P-. ft9 fH — of s 11 O 05 ^3 o •^ 05 Hm o £ os6 Effects of Ovarian Extracts 143 generally to cause an increase of force and rate of the rhythmic movements,and increased tone of the muscle. With hilurn ovarii the effect is inhibition
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