. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). probablyhave in diaschisis one of the most satisfactory exphma-tions for the apparent contradictions between symptomsand lesions that we fre(|uently observe, and by it possil3lywe may explain astereognosis and other sensory disturj)-ances following operations confined to the area of the 8 brain anterior to tlie central fissnre. In such operations,however, we must not discount the effect of exposure ofa considerable area of the brain, of the results of han-dling the brain during operation, and espe


. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). probablyhave in diaschisis one of the most satisfactory exphma-tions for the apparent contradictions between symptomsand lesions that we fre(|uently observe, and by it possil3lywe may explain astereognosis and other sensory disturj)-ances following operations confined to the area of the 8 brain anterior to tlie central fissnre. In such operations,however, we must not discount the effect of exposure ofa considerable area of the brain, of the results of han-dling the brain during operation, and especially theinterference with the circulation of adjoining regionscaused by the removal of a tumor or merely the ligationof vessels. The importance of the last procedure incausing symptoms has been demonstrated by the ligationof cortical vessels in the treatment of epilepsy. In this connection I would refer to the recent valuableLinacre lecture by .Sir Victor Horsley on the functionof the so-called motor area of the brain. He describes acase in whiili. Ijccause of the athetoid movements of the. Fig. 5.—Thrombosis of the inferior prtrosal mid cavi-rnous sinuses,catising lilie tliose of tumor, lasting aitovit a .year. left hand and later violent convulsive movements of thewhole left n]»per limb, he removed the entire motorregion for the upper liiiil) in the gyrus jH-ecentralis, asdctei-mined l^y the response to electric stimulation. Thewhole depth of this gyrus was without any iiijui-yto the neighljoring gyri or even to the vessels of the sulci,beyond the laceration of the smallest bianches enteringthe portion of gyrus removed. Although iitit germaneto the question under discussion here, it may Itc men-tioned that the spasmodic movements totally disap-peared fi-om the moment that the gyrus was removed,and have Iemained absent to the time of publication of 9 the paper (thirteen months), and a month after theoperation voluntary movements began to return and are


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