. The American journal of tropical medicine. dc .5d>> ?5. i0 o i 0 8 s J3 e 0 >> d0 a0 d0 bC 5 d £>> bO >> i >) « 2 d0 £ 0 EbC _£ 1 b£ _£0 fi s C ?5 B 00 tb 0 a ?Jl M 0 c 0 0 0 0 H I-; fa fe « z ?3 §gs a S J p H a o 3 (U Bo o 0 E0 03 J2bJ! bO 0 a) B0 c0 ** 5 C E0 >• B :< Z •z m M z z Z CO 02 Z 02 m -d J3 rt S0 0 3 0 -a , <^ 0 _o o m o1 ?•3 00 o a)a d 0 0 d .s a E1 _2 1 EC 0 3 2 ?3 3 •0 Ed •a (UX ?£ B & w Ul W U H 0 u ^ H S « D 366 DERMATITIS VENENATA 367 chloroform and ether. After shaking at intervals for twentyminutes, the solvents were poured into watch g
. The American journal of tropical medicine. dc .5d>> ?5. i0 o i 0 8 s J3 e 0 >> d0 a0 d0 bC 5 d £>> bO >> i >) « 2 d0 £ 0 EbC _£ 1 b£ _£0 fi s C ?5 B 00 tb 0 a ?Jl M 0 c 0 0 0 0 H I-; fa fe « z ?3 §gs a S J p H a o 3 (U Bo o 0 E0 03 J2bJ! bO 0 a) B0 c0 ** 5 C E0 >• B :< Z •z m M z z Z CO 02 Z 02 m -d J3 rt S0 0 3 0 -a , <^ 0 _o o m o1 ?•3 00 o a)a d 0 0 d .s a E1 _2 1 EC 0 3 2 ?3 3 •0 Ed •a (UX ?£ B & w Ul W U H 0 u ^ H S « D 366 DERMATITIS VENENATA 367 chloroform and ether. After shaking at intervals for twentyminutes, the solvents were poured into watch glasses and allowedto evaporate at room temperature. The residues obtained werevery small in amount, dark green and oily, excepting those fromwater, saline and carbon bisulphide, which were crystalline,greasy and transparent. Each of these residues were applied to the unbroken skin ofthe fore-arms of three non-susceptible individuals. Positiveresults were obtained with the residues from all the solvents. Fig. 2. Experimental Dermatitis Photograph of fading lesions on fore-arm of test individual, J. S. S., in experi-ment 16, taken twenty days after application of residues. excepting water, saline, benzine and the mixture of chloroformand ether. The fact that the untreated stem sap controls failedto produce dermatitis in these non-susceptible individuals, whileconcentrated extracts produced severe lesions, is a striking illus-tration of the quantitative nature of the reaction. One test individual (J. S. S.), on whom the dermatitis becameso severe as to require active treatment, was awakened on thefifth night by intense itching. There was marked local edemaaround all the points of application. Alcohol and ether were 368 JAMES S. SIMMONS AXD ZERA E. BOLIX applied followed b} a fatty ointment. On the following daymany new papules and vesicules were seen between old testlesions. Erjrthema and itching were more pronounced. On thetwentieth day there was still
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Keywords: ., bookcentury1900, bookdecade1920, booksubjecttropica, bookyear1921
