. The endocrine organs; an introduction to the study of internal secretion . FIG. 79.—Case of pituitary infantilism.(Byrom Bramwell.) The patient was27 when the photograph was height was 4 feet 1| the arrested development ofthe sexual organs, the deficiency ofhair, the adiposity, the slender limbsand digits, and the general approachto the feminine type of body. 112 The Endocrine Organs retrogression in the growth of the skeleton and body can generally beexpected. Thus the occurrence of hyperplasia and hyperpituitarism duringadolescence leading to a general overgrowth of
. The endocrine organs; an introduction to the study of internal secretion . FIG. 79.—Case of pituitary infantilism.(Byrom Bramwell.) The patient was27 when the photograph was height was 4 feet 1| the arrested development ofthe sexual organs, the deficiency ofhair, the adiposity, the slender limbsand digits, and the general approachto the feminine type of body. 112 The Endocrine Organs retrogression in the growth of the skeleton and body can generally beexpected. Thus the occurrence of hyperplasia and hyperpituitarism duringadolescence leading to a general overgrowth of the body and unusual growthof hair, and sometimes accompanied by sexual precocity, may be followedby glandular hypoplasia and diminution of the sexual instinct evenproceeding to impotence; as well as by excessive adiposity and the. FIG. 80.—X-ray photograph of hand from the case of infantilism shown in the precedingfigure. (Byrom Bramwell.) Notice the slender phalanges and the still detachedepiphyses. Reduced from 6J inches. assumption by the male of some of the feminine characteristics whichhave been above described as associated with hypopituitarism. This altera-tion in the signs of disease complicates the clinical features of manycases; the complications can only be unravelled by a careful study of thehistory of each case. In many instances where the affection begins with hyperplasia of thegland and subsequent changes produce destruction or degeneration of theenlarged organ, leading eventually to apituitarism, these changes mayoccupy years in their development, but the patient ultimately loses strengthand gradually wastes. Under such circumstances death results under Clinical Evidence regarding Functions of Pituitary 113 conditions which are probably analogous to those of cachexia Jtypophyseo-priva describe
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