Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . may contain a large amount of fibrous tissue andresemble a gumma. (2) Cold abscess, which is really a more diffuse formof caseous tuberculosis of muscle, and is generally due to extension ofosseous tuberculosis, arising in the bone to which the muscle or its sheathis attached. (3) Tuberculous interstitial fibroid myositis arising in musclescontiguous to tuberculous lesions and probably due to local disseminationof poisons produced in adjacent structures; this is the lesion observedin
Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . may contain a large amount of fibrous tissue andresemble a gumma. (2) Cold abscess, which is really a more diffuse formof caseous tuberculosis of muscle, and is generally due to extension ofosseous tuberculosis, arising in the bone to which the muscle or its sheathis attached. (3) Tuberculous interstitial fibroid myositis arising in musclescontiguous to tuberculous lesions and probably due to local disseminationof poisons produced in adjacent structures; this is the lesion observedin muscles lying next to tuberculous joints, glands, or bones. In ad-dition to the foregoing should be mentioned occasional instances ofdefinite miliary tuberculosis of muscle. Syphilis of muscle^ is of infrequent occurrence. An acute nonsup- Plantard, These de Paris, 1901. Lejars, La Sem. Med., June i, 1904,vol. xxiv, No. 22; Medical Press and Circular, June 22, 1904. ^ Bigot, These de Toulouse, 1901. Busse, Arch. f. klin. Chir., 1903, , Nos. I and 2. Fordyce, Jour, of Cutaneous Diseases, April, Fig. 391.—UbMiviNL. , A. Fragmenting muscle-fibers. B, B. Giant marrow cells. Thematrix in which A and B are situated is a granular partly calcifiedosteoid tissue. Till-; \ ML>;. ;«;/ purative diffuse interstitial myositis ( Kaonl) octurs during the secondarystage of s\ihilis,aii<l ii is possiMi- that tills forms the starting-point of amore chronic tibroid form, developing later in the infection. In boththe acute and chronic types of syphilitic myositis the alterations inthe muscle-hbers succeed the interstitial changes. Histologically theaffected muscle is first infiltrated by mononuclear cells and later anexcess of fibrous tissue is produced. The most common manifestation ofmuscle syphilis is the gumma, which in this structure does not differ fromsimilar lesions occurring elsewhere (|). 17Q). Leprosy and actinomycosis rarely involve the
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