. Alienist and neurologist. . tic form, no matter what its origin. It IS a singular fact that these transition forms producing the phenomenon ofsynapsis, are more prevalently found in animals under longer observation after the trauma;while in those killed or that died in the first period after the trauma in involutive formspredominate, that is to say, the ovules show atrophy and pigmentosis of the germinalvesicle. Cases occur, however, in which those forms with atrophy and pigmentosisof the germinal vesicle are intermixed with those in synapsis. At any rate, whateverinterpretation may be given
. Alienist and neurologist. . tic form, no matter what its origin. It IS a singular fact that these transition forms producing the phenomenon ofsynapsis, are more prevalently found in animals under longer observation after the trauma;while in those killed or that died in the first period after the trauma in involutive formspredominate, that is to say, the ovules show atrophy and pigmentosis of the germinalvesicle. Cases occur, however, in which those forms with atrophy and pigmentosisof the germinal vesicle are intermixed with those in synapsis. At any rate, whateverinterpretation may be given to the latter forms the fact remains that they only representa grave metabolic change of the ovule which must be considered as the effect of asimple functional disturbance capable of anatomic re-integration. Naturally, also, the chemical changes in the ovule following cerebral trauma Ili^diicHJbe transmitted deleteriously through the hereditary biological processes on the offspring. Page Nineteen THE ALIENIST AND NEUROLOGIST. i h9 Figs. 7, 8 and 9. Oocytes in stale of growth with ooplasm showing rarefaction; nucleolus ofJ^r^inative vesicle vacuolated; chromosomes disintegrated and variously distributed in the cytoplasmlibriu^psis) : Fig. 7, concentrated in one pole; Fig. 8, uniformly disseminated; Fig. 9, distributed atla periphery. From a bitch subjected to partial and bilateral destruction of the frontal lobes and^Killed 54 days later. X 900 diam. Iron hematoxylin. Page Twenty THE ALIENIST AND NEUROLOGIST It is not likely that a cell of such complexity, after such marked metabolic disturbance,will respond normally to the natural laws governing the perpetuation of the species. The possibility of a re-integration of the ovule in mammals is based not onlyon indirect deductions and analogous phenomena observed in birds, but also on directproof. Such, for instance, the negative findings in the bitches under longest observa-tion in which, as we have seen, the ovarian follicles wer
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