Fibroids and allied tumours (myoma and adenomyoma) : their pathology, clinical features and surgical treatment . mph-spaces are proof against hetero-topic invasion. Heterotopy of epithelium is not a pre-cancerous condition. Secondary carcinoma is not proved(Meyer). Epithelial heterotopy can occur in dystopic(embryonic) as well as in orthotopic (post-foetal, mature)epithelium. This behaviour of epithelium is not confinedto any particular tract or part of the body, but it has beenmore particularly studied in the genital tract, the alimentarysystem, the appendix (Lubarsch), gall-bladder (Lubarsch


Fibroids and allied tumours (myoma and adenomyoma) : their pathology, clinical features and surgical treatment . mph-spaces are proof against hetero-topic invasion. Heterotopy of epithelium is not a pre-cancerous condition. Secondary carcinoma is not proved(Meyer). Epithelial heterotopy can occur in dystopic(embryonic) as well as in orthotopic (post-foetal, mature)epithelium. This behaviour of epithelium is not confinedto any particular tract or part of the body, but it has beenmore particularly studied in the genital tract, the alimentarysystem, the appendix (Lubarsch), gall-bladder (Lubarsch), EPITHELIAL INVASION 29. kidney (Lubarsch), liver (Lubarsch), and skin (Friedlaender).In the Fallopian tubes it is especially common (in the formof mucosal heterotopv) in cases of tuberculosis and gonor-rhoea. In the uterus the invasion of mucosa is favouredbv the absence of a submucosa, and it can give rise tomucosal centrally situated growths, also to serosal peripher-ally situated ones. Heterotopy of serosal epithelium is the prob-able explanatiofi of the existence of the epithelial spaces and cysts in. Fig. 176.—Showing invasion of the underh-ing tissues by peritoneal epithelium.(After Sitzenfi-ey, Geh. und Gynak. Bd. Ixiv. Fig. 3, page 551.) .-?= flattened epithelium, the endothelium of the peritoneum j £= columnar epithelium;C=: connective-tissue cells commencing to form the cytogenous tissue. most of the extrauterine sivellings found between the rectum andthe genital tract. There is no doubt whatever about the possibility ofthe so-called endothelium of the peritoneum being able—when excited by inflammation, or under the influence otpregnancy (Alfieri)—to alter the character of the flattenedcells so that they become cylindrical and columnar (seeFigs. 176, 177, 178). This has been proved by repeatedinvestigations carried out by reliable observers. Moreover,it has also been conclusively shown that the connective 296 ADENOMYOMA CHAP. tissue which s


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectgynecologyoperative