Canine distemper, its complications, sequelae, and treatment . l moves about. At the end of eight or ten days, typicalvesico-pustules appear on the places of their election—namely, abdomen and thighs. The lungs become affected;the nasal discharge, at first slight, serous or sero-purulent,takes on a purulent character, and continues to flowfrom the nostrils, and the animal dies after a period offrom one to three weeks. The filterable virus or ultramicroscopic theory thusbecame established, and nearly all authorities still agreein ascribing as the direct cause of distemper a specific 14 ETIOLOGY


Canine distemper, its complications, sequelae, and treatment . l moves about. At the end of eight or ten days, typicalvesico-pustules appear on the places of their election—namely, abdomen and thighs. The lungs become affected;the nasal discharge, at first slight, serous or sero-purulent,takes on a purulent character, and continues to flowfrom the nostrils, and the animal dies after a period offrom one to three weeks. The filterable virus or ultramicroscopic theory thusbecame established, and nearly all authorities still agreein ascribing as the direct cause of distemper a specific 14 ETIOLOGY 15 ultra-visible virus, the exact nature of which has not yetbeen fully determined. That these germ-free fluids will, when inoculated, setup a disease corresponding very closely to distemperseems undoubted, and it was the realisation of this factwhich first prompted many bacteriologists to attempt toestablish a method of conferring an artificial immunity inthe healthy by experimentally inducing a benign attack. Unfortunately they were not very Fig. I.—Bacillus Bronchisepticus. Isolated by Ferry, and said to be the cause of 1,000 diameters. Bacterial Theory.—Numerous investigators have fromtime to time isolated various micro-organisms which theyhave considered to be the specific cause of distemper,but none appear to have been able to convince theveterinary medical world that they have- solved theproblem (see note on Bacteriology). Ferrys Bacillus Bronchisepticus.—However, in October,1908, after four years of continual experimental work, 16 CANINE DISTEMPER Dr. N. S. Ferry, an American veterinary surgeon,isolated the first pure culture of what he contended wasthe causative factor of the disease. To this organismFerry gave the name Bacillus bronchicanis, which namehe afterwards changed to B. bronchisepticus. Two other workers—namely, Dr. MGowan of Edin-burgh, and Dr. Torrey of New York—also independentlyisolated the identical organism,


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Keywords: ., bo, bookcentury1900, bookdecade1920, booksubjectdogs, bookyear1922